BDBM212068 US9290485, 100

SMILES CC(c1ccccc1)n1cc(cn1)C(=O)NCc1c(C)cc(N)nc1C

InChI Key InChIKey=DTLRUZKFZYHOBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212068   

TargetPlasma kallikrein(Human)
Novartis

US Patent
LigandPNGBDBM212068(US9290485, 100)
Affinity DataIC50: 642nMpH: 7.8 T: 2°CAssay Description:Enzymatic reactions were conducted in assay buffer , comprising 50 mM Hepes/NaOH at pH 7.8, 150 mM NaCl, 1 mM EDTA and 0.05% (w/v) CHAPS. For the det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
Go to US Patent