BDBM212413 US9290507, II-26

SMILES CN1CCN(CC1)c1cncc(c1)-c1cn(nn1)-c1cc(NC(=O)c2ccc(s2)C(C)(C)C)ccc1C

InChI Key InChIKey=PVNXSWRTWUFNTA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212413   

TargetSerine/threonine-protein kinase B-raf(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212413(US9290507, II-26)
Affinity DataIC50: 6nMpH: 7.5Assay Description:In a dilution series 10 uL/well of test substance solution are placed in a multiwell plate. The dilution series is selected so that generally a range...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
Go to US Patent