BDBM212425 US9290507, II-38

SMILES CN1CCN(CC1)c1cncc(c1)-c1cn(nn1)-c1cc(NC(=O)c2cc(C)n(n2)C(C)(C)C)ccc1C

InChI Key InChIKey=FXZNMBUEUHWGGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212425   

TargetSerine/threonine-protein kinase B-raf(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212425(US9290507, II-38)
Affinity DataIC50: 11nMpH: 7.5Assay Description:In a dilution series 10 uL/well of test substance solution are placed in a multiwell plate. The dilution series is selected so that generally a range...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent