BDBM212429 US9290507, II-42

SMILES CN1CCN(Cc2cc(oc2C(C)(C)C)C(=O)Nc2ccc(C)c(c2)-n2cc(nn2)-c2cncc(c2)N2CCOCC2)CC1

InChI Key InChIKey=QXPXRBCJHNJSGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 212429   

TargetSerine/threonine-protein kinase B-raf(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM212429(US9290507, II-42)
Affinity DataIC50: 16nMpH: 7.5Assay Description:In a dilution series 10 uL/well of test substance solution are placed in a multiwell plate. The dilution series is selected so that generally a range...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2017
Entry Details
US Patent