BDBM212959 US9278960, 4-43::US9663506, Example 4-43

SMILES CN1CCN(Cc2ccc3c(cc(nc3c2)C(N)=O)-c2ccc(F)cc2)CC1

InChI Key InChIKey=UXGSXTOQKTZHFK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 212959   

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212959(US9278960, 4-43 | US9663506, Example 4-43)
Affinity DataIC50: 252nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2019
Entry Details
US Patent

LigandPNGBDBM212959(US9278960, 4-43 | US9663506, Example 4-43)
Affinity DataIC50: 252nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2017
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM212959(US9278960, 4-43 | US9663506, Example 4-43)
Affinity DataIC50: 252nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent