BDBM213400 US9278978, 35

SMILES CNC(C)C(=O)Nc1cc(-c2ccncc2)c(-c2cncnc2)c(n1)C#Cc1ccccc1

InChI Key InChIKey=GZIWFKGJVGGFDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 213400   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 213400BDBM213400(US9278978, 35)
Affinity DataIC50: 103nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% TritonX100) for one...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [256-363](Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 213400BDBM213400(US9278978, 35)
Affinity DataIC50: 250nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% TritonX100) for one...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent