BDBM213508 US9278981, 100

SMILES CN[C@@H]1CCN(C1)c1ncc(cc1-c1cccnc1)C(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=INABTXFNRNUCJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 213508   

TargetTyrosine-protein kinase ABL1 [64-515](Human)
Novartis

US Patent
LigandPNGBDBM213508(US9278981, 100)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 uL of the compound pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2017
Entry Details
US Patent