BDBM215111 US9296736, 62::US9593129, Example 62

SMILES OC(=O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@]2(N(CC3CC3)C1=O)C(=O)Nc1cc(Cl)ccc21

InChI Key InChIKey=BJYAVSZQIJEQQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215111   

LigandChemical structure of BindingDB Monomer ID 215111BDBM215111(US9296736, 62 | US9593129, Example 62)
Affinity DataIC50: 90nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215111BDBM215111(US9296736, 62 | US9593129, Example 62)
Affinity DataIC50: 90nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
US Patent