BDBM215243 US9296736, 203::US9593129, Example 203

SMILES CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1[C@@H]([C@H](C[C@@](CC(O)=O)(OC)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1

InChI Key InChIKey=UXZAEZNRJHPRDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215243   

LigandChemical structure of BindingDB Monomer ID 215243BDBM215243(US9296736, 203 | US9593129, Example 203)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215243BDBM215243(US9296736, 203 | US9593129, Example 203)
Affinity DataIC50: 1nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
US Patent