BDBM215430 US9296736, 418::US9593129, Example 418

SMILES CC(C)N1C(=O)[C@H](CC(O)=O)C[C@H](c2cccc(Cl)c2)[C@@]1(C)c1ccc(Cl)cc1

InChI Key InChIKey=LQRDMEGRDDOARK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215430   

LigandChemical structure of BindingDB Monomer ID 215430BDBM215430(US9296736, 418 | US9593129, Example 418)
Affinity DataIC50: 18.3nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215430BDBM215430(US9296736, 418 | US9593129, Example 418)
Affinity DataIC50: 18.3nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
US Patent