BDBM218512 Chloridin::Daraprim::Malocide::Tindurine::US9284333, 16jw::US9884860, Example 16jw::pyrimethamine

SMILES CC[C@@H](NC(=O)c1cc(C(=O)NC(C)c2cnccn2)c2COCCn12)c1ccccc1

InChI Key InChIKey=ILVSFGPCXVPGET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218512   

TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM218512(pyrimethamine | Chloridin | Daraprim | Malocide | ...)
Affinity DataIC50: 2.86E+3nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM218512(pyrimethamine | Chloridin | Daraprim | Malocide | ...)
Affinity DataIC50: 2.86E+3nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent