BDBM218942 US9303033, W4, Table 13A, Compound 31

SMILES CNc1cc(nc2c(\C=C3/NC(=O)NC3=O)cnn12)-c1cccc(CNC(C)=O)c1

InChI Key InChIKey=XQYQZBHTFLLSGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218942   

TargetCasein kinase II subunit alpha/beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218942(US9303033, W4, Table 13A, Compound 31)
Affinity DataIC50: 10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
US Patent

TargetCasein kinase II subunit beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM218942(US9303033, W4, Table 13A, Compound 31)
Affinity DataIC50: 2.08E+3nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
US Patent