BDBM219447 US9303033, R24, Table 37A, Compound 121

SMILES O[C@H]1CCN(C1)C(=O)[C@@H](Nc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1ccccc1

InChI Key InChIKey=LUXDVYWBLACUHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 219447   

TargetCasein kinase II subunit alpha/beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM219447(US9303033, R24, Table 37A, Compound 121)
Affinity DataIC50: 100nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
US Patent

TargetCasein kinase II subunit beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM219447(US9303033, R24, Table 37A, Compound 121)
Affinity DataIC50: 1.00E+3nMpH: 7.0Assay Description:Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
US Patent