BDBM222005 3-(4-Bromo-phenyl)-1-(4-methanesulfonyl-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazole (10k)

SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)S(C)(=O)=O)c1ccc(Br)cc1

InChI Key InChIKey=WHKVOHPPRYWKLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222005   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

LigandPNGBDBM222005(3-(4-Bromo-phenyl)-1-(4-methanesulfonyl-phenyl)-5-...)
Affinity DataIC50:  4.85E+3nMAssay Description:The in vitro inhibition of ovine COX-1 and COX-2 was measured using an enzyme immuno assay (EIA) kit (Cayman Chemical, Ann Arbor, MI, USA) according ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Beni-Suef University

LigandPNGBDBM222005(3-(4-Bromo-phenyl)-1-(4-methanesulfonyl-phenyl)-5-...)
Affinity DataIC50:  630nMAssay Description:The in vitro inhibition of ovine COX-1 and COX-2 was measured using an enzyme immuno assay (EIA) kit (Cayman Chemical, Ann Arbor, MI, USA) according ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed