BDBM222473 US9315489, 9

SMILES Fc1cc(NC(=O)c2cccc(c2)-c2cncnc2)ccc1OC(F)(F)F

InChI Key InChIKey=RLLXECRBCPORMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222473   

TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM222473(US9315489, 9)
Affinity DataIC50:  22nMpH: 7.5 T: 2°CAssay Description:For determination of ABL kinase activity, the radiometric filter-binding assay was used. The assay was performed by mixing 10 μL of the compound p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent