BDBM22298 N-{2-[2-(4-chlorophenyl)-1H-indol-3-yl]ethyl}-4-pentylbenzene-1-sulfonamide::tryptamine sulfonamide, 37h

SMILES CCCCCc1ccc(S(=O)(=O)NCCc2c(-c3ccc(Cl)cc3)[nH]c3ccccc23)cc1

InChI Key InChIKey=JVKZLEZXLNTXPZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22298   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rabbit)
Bristol Myers Squibb

LigandChemical structure of BindingDB Monomer ID 22298BDBM22298(N-{2-[2-(4-chlorophenyl)-1H-indol-3-yl]ethyl}-4-pe...)
Affinity DataIC50: 32nMAssay Description:The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2008
Entry Details Article
PubMed