BDBM224574 US10202383, Example 2(9)::US9321791, 2(9)::US9556175, 2(9)

SMILES COCCn1c(=O)n(C)c2nc(N3CCCC(N)C3)n(Cc3ccccc3C#N)c2c1=O

InChI Key InChIKey=RGFSTPHASBPVBC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224574   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224574(US10202383, Example 2(9) | US9321791, 2(9) | US955...)
Affinity DataIC50:  264nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224574(US10202383, Example 2(9) | US9321791, 2(9) | US955...)
Affinity DataIC50:  264nMAssay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224574(US10202383, Example 2(9) | US9321791, 2(9) | US955...)
Affinity DataIC50:  264nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent