BDBM22532 4-Benzyl-1H-imidazole derivative, 13::4-benzyl-1H-imidazole

SMILES C(c1cnc[nH]1)c1ccccc1

InChI Key InChIKey=HREUGOAZLRNTEM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 22532   

TargetTrace amine-associated receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM22532(4-benzyl-1H-imidazole | 4-Benzyl-1H-imidazole deri...)
Affinity DataKi:  20nMAssay Description:Displacement of (S)-4-(2,4-difluorophenyl-3-tritio) -4,5-dihydro-2-oxazolamine from human TAAR1 receptor expressed in HEK293 cells after 90 mins by b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vu University Amsterdam

LigandPNGBDBM22532(4-benzyl-1H-imidazole | 4-Benzyl-1H-imidazole deri...)
Affinity DataKi:  162nM ΔG°:  -9.26kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed