BDBM22577 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}-N-[(1S)-2-hydroxy-1-phenylethyl]acetamide::CHEMBL277006::alpha-substituted indomethacin ethanolamide, 17
SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)N[C@H](CO)c3ccccc3)c2c1
InChI Key InChIKey=HBCGELQJRSFUJZ-XMMPIXPASA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 22577
Affinity DataIC50: <1.30E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: 85nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test co mpounds for 20 min and then analyzed for remaining COX activity by t...More data for this Ligand-Target Pair
Affinity DataIC50: <1.30E+3nMAssay Description:Inhibitory concentration of the compound against wild type murine Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibitory concentration against human Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibitory concentration against human prostaglandin G/H synthase 2More data for this Ligand-Target Pair