BDBM227269 US9328106, 220

SMILES CO[C@H]1CO[C@@H](CC[C@H]1N)c1c(NC(=O)c2nc(sc2N)-c2ccccc2C(F)(F)F)cnn1C

InChI Key InChIKey=LTYWLVJVWTVLAK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227269   

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

US Patent
LigandPNGBDBM227269(US9328106, 220)
Affinity DataKi:  0.0830nM ΔG°:  -13.7kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
US Patent