BDBM228541 US9340555, 27

SMILES COC(=O)CN(CCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1)CC(=O)OC

InChI Key InChIKey=OYGVKPPKBAPROS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 228541   

TargetVascular endothelial growth factor receptor 1(Human)
Allergan

US Patent
LigandPNGBDBM228541(US9340555, 27)
Affinity DataIC50: 11nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30 μg of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM228541(US9340555, 27)
Affinity DataIC50: 16nMpH: 7.2 T: 2°CAssay Description:Kinase assays were performed in 96 well microtiter plates that were coated overnight with 30 μg of poly-Glu-Tyr (4:1) in 10 mM Phosphate Buffered ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 1(Human)
Allergan

US Patent
LigandPNGBDBM228541(US9340555, 27)
Affinity DataIC50: 17nMAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of PDGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
US Patent