BDBM228871 US9328099, 2-2

SMILES CC(C)(C)OC(=O)N1CCC(CC#N)(CC1)n1cc(C(N)=O)c(Nc2ccc(Br)cc2)n1

InChI Key InChIKey=VQWRDWJBZRNERE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228871   

TargetTyrosine-protein kinase JAK1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM228871(US9328099, 2-2)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The reactions employed a common peptide substrate, LCB-EQEDEPEGDYFEWLW-NH2 (in-house). The basic assay protocol is as follows: First, 250 nL of dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM228871(US9328099, 2-2)
Affinity DataIC50: 23nMT: 2°CAssay Description:The reactions employed a common peptide substrate, LCB-EQEDEPEGDYFEWLW-NH2 (in-house). The basic assay protocol is as follows: First, 250 nL of dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details
US Patent