BDBM22919 1-[1-hydroxy-4-(naphthalen-1-yl)butan-2-yl]-1H-imidazole-4-carboxamide::CHEMBL327830::FR230513::imidazole-4-carboxamide derivative, 3

SMILES NC(=O)c1cn(cn1)C(CO)CCc1cccc2ccccc12

InChI Key InChIKey=URGFTPMACWKJKU-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 22919   

TargetAdenosine deaminase(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM22919(1-[1-hydroxy-4-(naphthalen-1-yl)butan-2-yl]-1H-imi...)
Affinity DataKi:  680nM ΔG°:  -8.32kcal/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
TargetAdenosine deaminase(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM22919(1-[1-hydroxy-4-(naphthalen-1-yl)butan-2-yl]-1H-imi...)
Affinity DataKi:  680nMAssay Description:Binding affinity towards adenosine deaminaseMore data for this Ligand-Target Pair
TargetAdenosine deaminase(Homo sapiens (Human))
Fujisawa Pharmaceutical

LigandPNGBDBM22919(1-[1-hydroxy-4-(naphthalen-1-yl)butan-2-yl]-1H-imi...)
Affinity DataIC50:  570nMAssay Description:Inhibitory concentration against adenosine deaminaseMore data for this Ligand-Target Pair