BDBM22979 CHEMBL148629::Meclofenamic acid derivative, 31::methyl 2-({2-[(2,6-dichloro-3-methylphenyl)amino]phenyl}formamido)acetate
SMILES COC(=O)CNC(=O)c1ccccc1Nc1c(Cl)ccc(C)c1Cl
InChI Key InChIKey=YMFGAYPNXNJNBI-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 22979
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of the ovine Prostaglandin G/H synthase 1 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 70nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair