BDBM231671 Ethyl 2-(3-(5-(trifluoromethyl)-1H-pyrazol-3-yl)phenoxy)acetate (3b)

SMILES CCOC(=O)COc1cccc(-c2cc(C(F)(F)F)[nH]n2)c1

InChI Key InChIKey=FEHKEASGFBWIGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231671   

TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (strain K12))
AstraZeneca

LigandChemical structure of BindingDB Monomer ID 231671BDBM231671(Ethyl 2-(3-(5-(trifluoromethyl)-1H-pyrazol-3-yl)ph...)
Affinity DataIC50: 80nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
AstraZeneca

LigandChemical structure of BindingDB Monomer ID 231671BDBM231671(Ethyl 2-(3-(5-(trifluoromethyl)-1H-pyrazol-3-yl)ph...)
Affinity DataIC50: 1.10E+4nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed