BDBM231672 Ethyl 2-(3-(3-(difluoromethyl)-1H-pyrazol-5-yl)phenoxy)acetate (3c)

SMILES CCOC(=O)COc1cccc(-c2cc(C(F)F)n[nH]2)c1

InChI Key InChIKey=RLGVJMICKNVIIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231672   

TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (strain K12))
AstraZeneca

LigandChemical structure of BindingDB Monomer ID 231672BDBM231672(Ethyl 2-(3-(3-(difluoromethyl)-1H-pyrazol-5-yl)phe...)
Affinity DataIC50: 1.00E+3nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
AstraZeneca

LigandChemical structure of BindingDB Monomer ID 231672BDBM231672(Ethyl 2-(3-(3-(difluoromethyl)-1H-pyrazol-5-yl)phe...)
Affinity DataIC50: 5.90E+4nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed