BDBM233025 N-[4-(Benzyloxy)phenyl]imidodicarbonimidic diamide hydrochloride (B1-01)

SMILES NC(=N)NC(=N)Nc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=CTMXZJFKGBQCRM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 233025   

TargetDihydrofolate reductase(Pneumocystis carinii)
Institute of Chemical Technology

LigandPNGBDBM233025(N-[4-(Benzyloxy)phenyl]imidodicarbonimidic diamide...)
Affinity DataIC50: 1.32E+5nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Institute of Chemical Technology

LigandPNGBDBM233025(N-[4-(Benzyloxy)phenyl]imidodicarbonimidic diamide...)
Affinity DataIC50: 1.32E+5nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mycobacterium avium)
Institute of Chemical Technology

LigandPNGBDBM233025(N-[4-(Benzyloxy)phenyl]imidodicarbonimidic diamide...)
Affinity DataIC50: 1.32E+5nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Institute of Chemical Technology

LigandPNGBDBM233025(N-[4-(Benzyloxy)phenyl]imidodicarbonimidic diamide...)
Affinity DataIC50: 1.32E+5nMAssay Description:The synthesized compounds were evaluated for their ability to inhibit DHFR from pc, tg, ma, and rl using a continuous spectrophotometric assay measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed