BDBM23355 BDBM25327::US8846656, 46-C

SMILES COc1ccc(C)c(N2CCc3nc(-c4c(C)ccc5[nH]ncc45)cc(C)c3C2)c1

InChI Key InChIKey=AUVDUYXOUMRHMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23355   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 23355BDBM23355(BDBM25327 | US8846656, 46-C)
Affinity DataIC50: 25nMAssay Description:Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 23355BDBM23355(BDBM25327 | US8846656, 46-C)
Affinity DataIC50: 27nMAssay Description:Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent