BDBM235011 4-(1-(2-bromo-6-(trifluoromethyl)benzyl)-4-fluoro-1H-indazol-3-yl)-5-fluoro-2-hydroxybenzoic acid (4A)::US9556168, 4A

SMILES OC(=O)c1cc(F)c(cc1O)-c1nn(Cc2c(Br)cccc2C(F)(F)F)c2cccc(F)c12

InChI Key InChIKey=KPHHIXOCRMMGTI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235011   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM235011(4-(1-(2-bromo-6-(trifluoromethyl)benzyl)-4-fluoro-...)
Affinity DataIC50:  4nMpH: 7.0Assay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent