BDBM235635 (E)-1-(2,4-dihydroxyphenyl)-3-(2-nitrophenyl)-2-propen-1-one (7)

SMILES Oc1ccc(C(=O)\C=C\c2ccccc2[N+]([O-])=O)c(O)c1

InChI Key InChIKey=PZNSXDODRVGONW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235635   

TargetBeta-secretase 1(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

LigandPNGBDBM235635((E)-1-(2,4-dihydroxyphenyl)-3-(2-nitrophenyl)-2-pr...)
Affinity DataIC50: 6.00E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2017
Entry Details Article
PubMed