BDBM235683 Estradiol-17β (3)::US9688816, A

SMILES C[C@]12CC[C@H]3[C@@H](CCC4=CC(O)=CCC34)[C@@H]1CCC2O

InChI Key InChIKey=SXIVSVSDFGYPBQ-NORZTXRYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 235683   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Balikesir University

LigandPNGBDBM235683(Estradiol-17β (3) | US9688816, A)
Affinity DataIC50:  1.00E+4nMAssay Description:CA activity was measured by the Maren method which is based on determination of the time required for the pH to decrease from 10.0 to 7.4 due to CO2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Balikesir University

LigandPNGBDBM235683(Estradiol-17β (3) | US9688816, A)
Affinity DataIC50:  4.39E+5nMAssay Description:CA activity was measured by the Maren method which is based on determination of the time required for the pH to decrease from 10.0 to 7.4 due to CO2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM235683(Estradiol-17β (3) | US9688816, A)
Affinity DataIC50:  1nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM235683(Estradiol-17β (3) | US9688816, A)
Affinity DataIC50:  15nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM235683(Estradiol-17β (3) | US9688816, A)
Affinity DataIC50:  7nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM235683(Estradiol-17β (3) | US9688816, A)
Affinity DataIC50:  6.60nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM235683(Estradiol-17β (3) | US9688816, A)
Affinity DataIC50:  10nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM235683(Estradiol-17β (3) | US9688816, A)
Affinity DataIC50:  8.20nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent