BDBM236119 US9365563, E2::US9878991, Compound E2

SMILES OC[C@@H](O)c1cnc(C2=CCN(CC2)C(=O)Nc2ccc(OC(F)(F)F)cc2)c(Cl)c1

InChI Key InChIKey=LFNMJQYGWLSCTA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 236119   

LigandPNGBDBM236119(US9365563, E2 | US9878991, Compound E2)
Affinity DataIC50: 107nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

LigandPNGBDBM236119(US9365563, E2 | US9878991, Compound E2)
Affinity DataIC50: 20.3nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent

LigandPNGBDBM236119(US9365563, E2 | US9878991, Compound E2)
Affinity DataIC50: 107nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

LigandPNGBDBM236119(US9365563, E2 | US9878991, Compound E2)
Affinity DataIC50: 20.3nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent