BDBM23728 2-(2-methoxyphenoxy)-N'-(thiophen-2-ylcarbonyl)acetohydrazide::N -[2-(2-methoxyphenoxy)acetyl]thiophene-2-carbohydrazide::cid_730175::thiophene-2-carbohydrazide, 12

SMILES COc1ccccc1OCC(=O)NNC(=O)c1cccs1

InChI Key InChIKey=IMYKQWRCRSFFBU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23728   

TargetCoagulation factor XII(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM23728(N -[2-(2-methoxyphenoxy)acetyl]thiophene-2-carbohy...)
Affinity DataIC50: 4.70E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay
TargetNeutrophil elastase(Human)
Montana State University

LigandPNGBDBM23728(N -[2-(2-methoxyphenoxy)acetyl]thiophene-2-carbohy...)
Affinity DataKi:  820nM ΔG°:  -8.30kcal/molepH: 7.5 T: 2°CAssay Description:HTS was performed in black flat-bottom 96-well microtiter plates. The reaction was initiated by addition of elastase substrate to the reaction buffer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed