BDBM239060 US10227295, Compound 9b::US9409858, 9b::US9751832, Compound 9b::US9956192, Compound 9b

SMILES Cc1ccnc(NC(=O)NCc2ccc(cc2)C(=O)NO)c1

InChI Key InChIKey=KRTQXYIQFGQFJS-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 239060   

TargetHistone deacetylase 6(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239060(US9409858, 9b | US9751832, Compound 9b | US1022729...)
Affinity DataIC50: 2.20nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239060(US9409858, 9b | US9751832, Compound 9b | US1022729...)
Affinity DataIC50: 2.20nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239060(US9409858, 9b | US9751832, Compound 9b | US1022729...)
Affinity DataIC50: 2.20nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239060(US9409858, 9b | US9751832, Compound 9b | US1022729...)
Affinity DataIC50: 2.20nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239060(US9409858, 9b | US9751832, Compound 9b | US1022729...)
Affinity DataIC50: 579nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239060(US9409858, 9b | US9751832, Compound 9b | US1022729...)
Affinity DataIC50: 579nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239060(US9409858, 9b | US9751832, Compound 9b | US1022729...)
Affinity DataIC50: 579nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239060(US9409858, 9b | US9751832, Compound 9b | US1022729...)
Affinity DataIC50: 579nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent