BDBM239156 6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-methylcoumarine (1b)

SMILES Cc1ncc(n1CCOc1ccc2oc(=O)cc(C)c2c1)[N+]([O-])=O

InChI Key InChIKey=HNNWVMYYQQKICE-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 239156   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi:  400nM ΔG°:  -8.11kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi:  430nM ΔG°:  -8.07kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi:  470nM ΔG°:  -8.02kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi:  800nM ΔG°:  -7.73kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi:  820nM ΔG°:  -7.71kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi:  2.63E+3nM ΔG°:  -7.07kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi:  5.30E+4nM ΔG°:  -5.42kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi: >2.00E+5nM ΔG°: >-4.69kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi: >2.00E+5nM ΔG°: >-4.69kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi: >2.00E+5nM ΔG°: >-4.69kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier

LigandPNGBDBM239156(6-O-[2-(2-methyl-5-nitro-imidazol-1-yl)ethyl]-4-me...)
Affinity DataKi: >2.00E+5nM ΔG°: >-4.69kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed