BDBM239597 US9394309, 50::US9394309, 93

SMILES Cc1ccc(NC(=O)c2cc(cc(c2)C(C)(C)C)C#N)cc1-n1ccn2nc(cc12)-c1cccnc1

InChI Key InChIKey=XKUVDPRDXVKPSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239597   

TargetAngiopoietin-1 receptor [776-1124](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM239597(US9394309, 93 | US9394309, 50)
Affinity DataIC50: 1.20nMpH: 7.0 T: 2°CAssay Description:For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetAngiopoietin-1 receptor [776-1124](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM239597(US9394309, 93 | US9394309, 50)
Affinity DataIC50: 19nMpH: 7.0 T: 2°CAssay Description:For the assay, 50 nl of a 100-fold concentrated solution of the respective test substance in DMSO were pipetted into a black low-volume 384-well micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent