BDBM239937 US9403767, 121::US9403767, 123

SMILES CN(C)C(=O)CN(C)C1(CCC(CC1)(N(C)C)c1ccccc1)c1ccccc1

InChI Key InChIKey=QBKKGYWLVOYENH-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 239937   

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239937(US9403767, 123 | US9403767, 121)
Affinity DataKi:  230nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239937(US9403767, 123 | US9403767, 121)
Affinity DataKi:  1.43E+3nM ΔG°:  -7.97kcal/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM239937(US9403767, 123 | US9403767, 121)
Affinity DataKi:  2.60E+3nM ΔG°:  -7.61kcal/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent