BDBM242131 US9415055, 2,4-dichloro-N-(2-morpholino-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)benzamide::US9593105, 132

SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1ccc(Cl)cc1Cl)N1CCOCC1

InChI Key InChIKey=LPWJFAZRQDMPJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 242131   

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM242131(US9415055, 2,4-dichloro-N-(2-morpholino-2-(2-(trif...)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetP2X purinoceptor 7(Human)
H. Lundbeck

US Patent
LigandPNGBDBM242131(US9415055, 2,4-dichloro-N-(2-morpholino-2-(2-(trif...)
Affinity DataIC50: 12nMAssay Description:Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent