BDBM244106 US9428491, 1.1::US9428491, 1.1: 2HCl::US9428491, 1.1: naphtalene-1,5-disulfonic acid
SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1nc(c[nH]1)C#CC#Cc1ccc(cc1)-c1c[nH]c(n1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C
InChI Key InChIKey=AUDQGNZRGAPQBI-YDPTYEFTSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 244106
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00310nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00340nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
TBA
US Patent
TBA
US Patent
Affinity DataIC50: 0.00400nMT: 2°CAssay Description:Solutions of the tested compounds in DMEM medium {DMEM) 1x; Source: Cellgro; Catalogue: 10-013-CV} were prepared immediately before use. Eleven seria...More data for this Ligand-Target Pair
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute
Curated by ChEMBL
Chemical Diversity Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.407nMAssay Description:Inhibition of HCV genotype 5a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute
Curated by ChEMBL
Chemical Diversity Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0840nMAssay Description:Inhibition of HCV genotype 2a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute
Curated by ChEMBL
Chemical Diversity Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of HCV genotype 4a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute
Curated by ChEMBL
Chemical Diversity Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.215nMAssay Description:Inhibition of HCV genotype 1a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute
Curated by ChEMBL
Chemical Diversity Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.00500nMAssay Description:Inhibition of HCV genotype 1b NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by Celltiter Glo a...More data for this Ligand-Target Pair
TargetNonstructural protein 5A(Hepatitis C virus)
Chemical Diversity Research Institute
Curated by ChEMBL
Chemical Diversity Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.45nMAssay Description:Inhibition of HCV genotype 3a NS5A infected in Huh7 cells assessed as reduction in viral replication incubated 3 days and measured by bright Glo-luci...More data for this Ligand-Target Pair