BDBM244241 US9546173, cmpd 161::n-((1r,2r)-2-(dimethylamino)cyclohexyl)-5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide

SMILES CN(C)[C@@H]1CCCC[C@H]1NC(=O)N1Cc2nc(Nc3ccccc3)ncc2C1(C)C

InChI Key InChIKey=GGSXHTXJUORVAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244241   

TargetRibosomal protein S6 kinase alpha-3(Human)
Novartis

US Patent
LigandPNGBDBM244241(n-((1r,2r)-2-(dimethylamino)cyclohexyl)-5,5-dimeth...)
Affinity DataIC50: 8.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Novartis

US Patent
LigandPNGBDBM244241(n-((1r,2r)-2-(dimethylamino)cyclohexyl)-5,5-dimeth...)
Affinity DataIC50: 1.25E+5nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent