BDBM244659 US10226449, cpd 269::US9428502, 269

SMILES Cc1n[nH]c(C)c1-c1cccc(c1)C(=O)N1CC(C1)c1ccc(cc1)C#N

InChI Key InChIKey=FMYFKMTVYCTAAO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 244659   

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM244659(US9428502, 269 | US10226449, cpd 269 | US202500179...)
Affinity DataIC50: 5.00E+4nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM244659(US9428502, 269 | US10226449, cpd 269 | US202500179...)
Affinity DataIC50: 5.00E+4nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetFatty acid synthase(Human)
3-V Biosciences

US Patent
LigandPNGBDBM244659(US9428502, 269 | US10226449, cpd 269 | US202500179...)
Affinity DataIC50: 5.00E+4nMAssay Description:Determination of FASN biochemical activity: The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent