BDBM245562 US9428508, 16

SMILES CNC(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCOCC3)c3OCCOc23)nc2NCCc12

InChI Key InChIKey=GMWQBALBFOYABZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245562   

TargetFocal adhesion kinase 1(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM245562(US9428508, 16)
Affinity DataIC50: 500nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetProtein-tyrosine kinase 2-beta(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM245562(US9428508, 16)
Affinity DataIC50: 200nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent