BDBM245567 US9428508, 22

SMILES CNC(=O)c1ccccc1Nc1nc(Nc2cccc3n(CCCN4CCOCC4)ccc23)nc2NCCc12

InChI Key InChIKey=YLRSENMGFOEJDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245567   

TargetFocal adhesion kinase 1(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM245567(US9428508, 22)
Affinity DataIC50: 100nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetProtein-tyrosine kinase 2-beta(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM245567(US9428508, 22)
Affinity DataIC50: 200nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent