BDBM245645 US9428508, 100

SMILES COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)C(C)C)n1)N1CCOCC1

InChI Key InChIKey=JJZGVHZVTGHJEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245645   

TargetFocal adhesion kinase 1(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM245645(US9428508, 100)
Affinity DataIC50: 20nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent

TargetProtein-tyrosine kinase 2-beta(Human)
Centaurus Biopharma

US Patent
LigandPNGBDBM245645(US9428508, 100)
Affinity DataIC50: 50nMAssay Description:To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
US Patent