BDBM245739 US9428511, 31

SMILES COc1ccc(cn1)-c1cn2ncc(C(N)=O)c(N[C@H]3CN(C[C@H]3C)C(=O)C3(CC3)C#N)c2n1

InChI Key InChIKey=JZOLJUPLJHLUMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245739   

TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM245739(US9428511, 31)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM245739(US9428511, 31)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
Go to US Patent