BDBM245779 US9428511, 72

SMILES CC[C@H]1CN(C[C@H]1Nc1c(cnn2cc(nc12)-c1cn[nH]c1)C(N)=O)C(=O)C1(CC1)C#N

InChI Key InChIKey=PPRAAYSRROVMEX-SWLSCSKDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245779   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM245779(US9428511, 72)
Affinity DataIC50:  3nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM245779(US9428511, 72)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:The assay reactions were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent