BDBM24569 (1R)-1-{[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]methyl}dodecyl N-formylglycinate::(2S)-1-[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]tridecan-2-yl 2-formamidoacetate::Orlistat derivative, 15f::Orlistat derivative, 17a

SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CC)OC(=O)CNC=O

InChI Key InChIKey=QUCZRYAJOAFMJB-FHWLQOOXSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24569   

TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24569((1R)-1-{[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50:  790nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
The Burnham Institute For Medical Research

LigandPNGBDBM24569((1R)-1-{[(2S,3S)-3-ethyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50:  230nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed