BDBM246646 US9550763, Compound I-298

SMILES CN(C)C(=O)CNC(=O)c1cn(Cc2ccc(Cl)cc2)c(Nc2ccc(Oc3ccc(C)nn3)cc2)nc1=O

InChI Key InChIKey=BHMZWHYEKQZKGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246646   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM246646(US9550763, Compound I-298)
Affinity DataIC50: 23nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent