BDBM247795 US9434719, 398 as TFA salt

SMILES C[C@@H](F)[C@H]1COC(=O)N1c1nc(N[C@@H](C)c2cc(on2)-c2ccc(C)cc2)ncc1F

InChI Key InChIKey=VTOAZJNVLIGQLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 247795   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Novartis

US Patent
LigandPNGBDBM247795(US9434719, 398 as TFA salt)
Affinity DataIC50: 39nMpH: 7.5 T: 2°CAssay Description:The IDH1 (R132H) mutant catalyzes the reduced form of NADP+ (NADPH) and α-ketoglutarate (α-KG) to form nicotinamide adenine dinucleotide ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent