BDBM248905 US9434725, 136
SMILES CCn1cc(cn1)-c1cc2n(ncc2cn1)-c1cccc(n1)N1CC[C@@H](N)C1
InChI Key InChIKey=WXBFQEMPNLLMNB-MRXNPFEDSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 248905
Affinity DataKi: 0.615nM ΔG°: -12.6kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 2.05nM ΔG°: -11.8kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair
Affinity DataKi: 17.3nM ΔG°: -10.6kcal/molepH: 7.2 T: 2°CAssay Description:PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J. F., a...More data for this Ligand-Target Pair